Extra Health:
Use a text editor to edit the "gamestat.ini" file in the "\spider-man 2\system" 
folder. Locate the line: 

MaxHealth=100 // 200 is upgraded value 
and change it to 

MaxHealth=1000 // 2000 is upgraded value 
Save the modified file, then use a text editor to edit the "game?.ini" file in 
the "\spider-man 2\system" folder that corresponds to your saved game. Locate 
the line: 

Health=100MaxHealth=100 
and change it to: 

Health=1000 MaxHealth=1000 
Note: This procedure involves editing game files; create a backup copy of the files 
before proceeding. If you have not saved the game yet, start a new game and 
play until you can do so. Use a text editor to edit the "gamestat.ini" file in 
the "\spider-man 2\system" folder. Locate the line: 

MaxHealth=100 // 200 is upgraded value 
and change it to 

MaxHealth=1000 // 2000 is upgraded value 
Save the modified file, then use a text editor to edit the "game?.ini" file in 
the "\spider-man 2\system" folder that corresponds to your saved game. Locate 
the line: 

Health=100MaxHealth=100 
and change it to: 

Health=1000 MaxHealth=1000

Crawl On Wall Faster:
Get on a wall and begin crawling and jumping at the same time. You will climb up 
the wall faster. This is useful when you face Puma.

All Spiders And Prisoners:
This procedure involves editing game files; create a backup copy of the files 
before proceeding. If you have not saved the game yet, start a new game and 
play until you can do so. Use a text editor to edit the 'game<number>' file in 
the '\spider-man 2\system' folder that corresponds to your saved game. Delete all 
the spider and prisoner information. Save it and play the game with all prisoners 
and spiders. 

Free Ride:
To get around the city quickly, get on top of a vehicle and enjoy the ride.

Travel Faster:
Because you cannot swing freely without the Spidey targets, you can zip. First, zip 
as far from the building as possible then quickly turn to another building before 
you reach the first one. Keep doing this so you can travel faster. 

Level skip:
Note: This procedure involves editing game files; create a backup copy of the files 
before proceeding. If you have not saved the game yet, start a new game and 
play until you can do so. Use a text editor to edit the "game<number>" file in 
the "\spider-man 2\system" folder that corresponds to your saved game. Make the 
following changes. 

LocationX Number pending/Change to 0
LocationY Number pending/Change to 0
LocationZ Number pending/Change to 0 
LevelComplete0=0/1 Change to 1 (do to all levels wanted completed) 
LevelComplete1=0/1 
Find the file "maps.int". Find the name of the map level you want, and replace it in 
the game<number> file at the "Map" line. Note: During this process keep all 
equals signs but not the minuses.